
Are you the hunter or the prey? It's a tough world out there. Here's how to deal with it:
Even since the release of Mk 1 Grenades, in the harsh and distrustful world of Arkham Horror: The Competitive Card Game* this hidden gem still truly is the best PVP card in the game.
To get rid of annoying extras and side-kicks for good you will essentially only need a copy of Teamwork and wait for your nemesis' most vulnerable moment. (Note that you really want to be sure you can go all the way though - otherwise you have just gifted them 2 XP, and you don't want anyone but yourself to take the lead, do you?)
Of course, if your investigator already has access to Teamwork obvious finishers in your card pool might include "You handle this one!", Dynamite Blast, Shotgun, Sawed-Off Shotgun, and Mk 1 Grenades (for which you optimally pay for with their own money). Otherwise, sneak it in your deck being Versatile.
And who knows, maybe you will find something interesting in your clingy human resources on the Black Market or get to liquidate their courage. Don't want to let them have their insurances lingering around, remember?
If they still have realistic chances of surviving the mythos phase, be sure to break a promise you made with Geas at the end of your turn. If that doesn't work, a bonus round gifted by The Gold Pocket Watch might do the trick.
Pretend to Safeguard that nosy cluever who denied you your Lone Wolf resource (three times in a row!) before Kicking the Hornet's Nest, just to be Elusive, Think on Your Feet, or Ethereal Slip away, letting the baddies finish the job. In the rare case they will see your evil plot coming and maintain distance you can still gather the filth and fix positioning with a well-timed Warning Shot.
Oh, and don't forget to cash in with Decorated Skull afterwards if you get close enough to enjoy the show.
*Seriously, if you hate your friends, just play solo.
UPDATE: Sadly, my proposition does not go through since this FAQ: arkhamdb.com