
This has been updated to match my "Signature Weakness Project." I have done my best to make sure that the original content isn't altered too much, out of respect for any comments.
Another bad, trauma-inducing weakness. Looking at the two elements, the effect and the discard condition, we get:
The effect: This Weakness has many of the same issues as Roland's Cover Up, although Jenny has a greater capacity for mental trauma, so a bad draw at the end of a scenario isn't quite as deadly. On the other hand, while Jenny's Weakness can always be resolved if you can get to it (no clue shenanigans), it does appear on the furthest location, which can be very bad in large or unusually-shaped maps, plus it goes into her discard pile when resolved for extra drawing possibilities. Any investigator can trigger this, although the and an Investigate test is a tougher nut to crack and more vulnerable to a bad location choice. Missing the test on Searching for Izzie effectively costs you an extra turn. Searching for Izzy can cost Jenny 2 Trauma if she gets defeated while it is out, adding injury to more injury. Since it's attached to a location, if the scenario discards locations, the Weakness will also get discarded, so that's nice. There are not many specific mitigating strategies besides making sure someone can pass that Investigate test and movement boosts like Nimble or Elusive (and maybe "I'm outta here!" to get back to a Resign point).
The discard condition: Get to the location, spend two actions, and succeed on an Investigate test.
Taking everything together, this is a way above average signature weakness, being very action intensive and subject to timing. It might be a little easier in higher player counts. It can end a campaign.
Box vs book Between the two signature weaknesses, the "book" set has an advantage (especially in solo), while the assets are about the same, although they do pretty different things. Players might well prefer the "book" to the "box," and who would want both?